The influence of the 5΄-terminal nucleotide on AgoshRNA activity and biogenesis: importance of the polymerase III transcription initiation site

Recent evidence indicates that shRNAs with a relatively short basepaired stem do not require Dicer processing, but instead are processed by the Argonaute 2 protein (Ago2). We named these molecules AgoshRNAs as both their processing and silencing function are mediated by Ago2. This alternative proces...

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Detalles Bibliográficos
Autores principales: Herrera-Carrillo, Elena, Gao, Zong-liang, Harwig, Alex, Heemskerk, Matthias T., Berkhout, Ben
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397164/
https://www.ncbi.nlm.nih.gov/pubmed/27928054
http://dx.doi.org/10.1093/nar/gkw1203

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397164/
https://www.ncbi.nlm.nih.gov/pubmed/27928054
http://dx.doi.org/10.1093/nar/gkw1203

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