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Conformational polymorphism or structural invariance in DNA photoinduced lesions: implications for repair rates

DNA photolesions constitute a particularly deleterious class of molecular defects responsible for the insurgence of a vast majority of skin malignant tumors. Dimerization of two adjacent thymines or cytosines mostly gives rise to cyclobutane pyrimidine dimers (CPD) and pyrimidine(6-4)pyrimidone 64-P...

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Detalles Bibliográficos
Autores principales: Dehez, François, Gattuso, Hugo, Bignon, Emmanuelle, Morell, Christophe, Dumont, Elise, Monari, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397166/
https://www.ncbi.nlm.nih.gov/pubmed/28334906
http://dx.doi.org/10.1093/nar/gkx148