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ADAR2 regulates RNA stability by modifying access of decay-promoting RNA-binding proteins

Adenosine deaminases acting on RNA (ADARs) catalyze the editing of adenosine residues to inosine (A-to-I) within RNA sequences, mostly in the introns and UTRs (un-translated regions). The significance of editing within non-coding regions of RNA is poorly understood. Here, we demonstrate that associa...

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Detalles Bibliográficos
Autores principales: Anantharaman, Aparna, Tripathi, Vidisha, Khan, Abid, Yoon, Je-Hyun, Singh, Deepak K., Gholamalamdari, Omid, Guang, Shuomeng, Ohlson, Johan, Wahlstedt, Helene, Öhman, Marie, Jantsch, Michael F., Conrad, Nicholas K., Ma, Jian, Gorospe, Myriam, Prasanth, Supriya G., Prasanth, Kannanganattu V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397167/
https://www.ncbi.nlm.nih.gov/pubmed/28053121
http://dx.doi.org/10.1093/nar/gkw1304