Cargando…
Iron mediates catalysis of nucleic acid processing enzymes: support for Fe(II) as a cofactor before the great oxidation event
Life originated in an anoxic, Fe(2+)-rich environment. We hypothesize that on early Earth, Fe(2+) was a ubiquitous cofactor for nucleic acids, with roles in RNA folding and catalysis as well as in processing of nucleic acids by protein enzymes. In this model, Mg(2+) replaced Fe(2+) as the primary co...
| Autores principales: | , , , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2017
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397171/ https://www.ncbi.nlm.nih.gov/pubmed/28334877 http://dx.doi.org/10.1093/nar/gkx171 |