DNA polymerase β uses its lyase domain in a processive search for DNA damage

DNA polymerase (Pol) β maintains genome fidelity by catalyzing DNA synthesis and removal of a reactive DNA repair intermediate during base excision repair (BER). Situated within the middle of the BER pathway, Pol β must efficiently locate its substrates before damage is exacerbated. The mechanisms o...

Descripción completa

Detalles Bibliográficos
Autores principales: Howard, Michael J., Rodriguez, Yesenia, Wilson, Samuel H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397181/
https://www.ncbi.nlm.nih.gov/pubmed/28119421
http://dx.doi.org/10.1093/nar/gkx047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397181/
https://www.ncbi.nlm.nih.gov/pubmed/28119421
http://dx.doi.org/10.1093/nar/gkx047

Ejemplares similares