Deletion of the rnl gene encoding a nick-sealing RNA ligase sensitizes Deinococcus radiodurans to ionizing radiation

Deinococcus radiodurans RNA ligase (DraRnl) seals 3΄-OH/5΄-PO(4) nicks in duplex nucleic acids in which the 3΄-OH nick terminus consists of two or more ribonucleotides. DraRnl exemplifies a widely distributed Rnl5 family of nick-sealing RNA ligases, the physiological functions of which are uncharted...

Descripción completa

Detalles Bibliográficos
Autores principales: Schmier, Brad J., Chen, Xinguo, Wolin, Sandra, Shuman, Stewart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397189/
https://www.ncbi.nlm.nih.gov/pubmed/28126918
http://dx.doi.org/10.1093/nar/gkx038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397189/
https://www.ncbi.nlm.nih.gov/pubmed/28126918
http://dx.doi.org/10.1093/nar/gkx038

Ejemplares similares