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Applicability of a computational design approach for synthetic riboswitches

Riboswitches have gained attention as tools for synthetic biology, since they enable researchers to reprogram cells to sense and respond to exogenous molecules. In vitro evolutionary approaches produced numerous RNA aptamers that bind such small ligands, but their conversion into functional riboswit...

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Detalles Bibliográficos
Autores principales: Domin, Gesine, Findeiß, Sven, Wachsmuth, Manja, Will, Sebastian, Stadler, Peter F., Mörl, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397205/
https://www.ncbi.nlm.nih.gov/pubmed/27994029
http://dx.doi.org/10.1093/nar/gkw1267