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Coordinated control of terminal differentiation and restriction of cellular plasticity

The acquisition of a specific cellular identity is usually paralleled by a restriction of cellular plasticity. Whether and how these two processes are coordinated is poorly understood. Transcription factors called terminal selectors activate identity-specific effector genes during neuronal different...

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Detalles Bibliográficos
Autores principales: Patel, Tulsi, Hobert, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397285/
https://www.ncbi.nlm.nih.gov/pubmed/28422646
http://dx.doi.org/10.7554/eLife.24100