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Modeling fructose-load-induced hepatic de-novo lipogenesis by model simplification
Hepatic de-novo lipogenesis is a metabolic process implemented in the pathogenesis of type 2 diabetes. Clinically, the rate of this process can be ascertained by use of labeled acetate and stimulation by fructose administration. A systems pharmacology model of this process is desirable because it fa...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397296/ https://www.ncbi.nlm.nih.gov/pubmed/28469410 http://dx.doi.org/10.1177/1177625017690133 |