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Mechanical Strain Promotes Oligodendrocyte Differentiation by Global Changes of Gene Expression

Differentiation of oligodendrocyte progenitor cells (OPC) to oligodendrocytes and subsequent axon myelination are critical steps in vertebrate central nervous system (CNS) development and regeneration. Growing evidence supports the significance of mechanical factors in oligodendrocyte biology. Here,...

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Detalles Bibliográficos
Autores principales: Jagielska, Anna, Lowe, Alexis L., Makhija, Ekta, Wroblewska, Liliana, Guck, Jochen, Franklin, Robin J. M., Shivashankar, G. V., Van Vliet, Krystyn J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397481/
https://www.ncbi.nlm.nih.gov/pubmed/28473753
http://dx.doi.org/10.3389/fncel.2017.00093