Opacification Domain of Serum Opacity Factor Inhibits Beta-Hemolysis and Contributes to Virulence of Streptococcus pyogenes

Serum opacity factor (SOF) is a cell surface virulence factor made by the human pathogen Streptococcus pyogenes. We found that S. pyogenes strains with naturally occurring truncation mutations in the sof gene have markedly enhanced beta-hemolysis. Moreover, deletion of the sof gene in a SOF-positive...

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Detalles Bibliográficos
Autores principales: Zhu, Luchang, Olsen, Randall J., Musser, James M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397570/
https://www.ncbi.nlm.nih.gov/pubmed/28435893
http://dx.doi.org/10.1128/mSphereDirect.00147-17

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397570/
https://www.ncbi.nlm.nih.gov/pubmed/28435893
http://dx.doi.org/10.1128/mSphereDirect.00147-17

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