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MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis

Monocytes and macrophages are key mediators of inflammation in rheumatoid arthritis (RA). Their persistence at the inflammatory site is likely to contribute to immunopathology. We sought to characterise one mechanism by which persistence may be achieved: resistance to apoptosis and the role of mir-1...

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Detalles Bibliográficos
Autores principales: Rajasekhar, Megha, Olsson, Anton M., Steel, Kathryn J.A., Georgouli, Mirella, Ranasinghe, Ushan, Brender Read, Christine, Frederiksen, Klaus S., Taams, Leonie S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397583/
https://www.ncbi.nlm.nih.gov/pubmed/28118944
http://dx.doi.org/10.1016/j.jaut.2017.01.002