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MicroRNA-155 contributes to enhanced resistance to apoptosis in monocytes from patients with rheumatoid arthritis
Monocytes and macrophages are key mediators of inflammation in rheumatoid arthritis (RA). Their persistence at the inflammatory site is likely to contribute to immunopathology. We sought to characterise one mechanism by which persistence may be achieved: resistance to apoptosis and the role of mir-1...
Autores principales: | Rajasekhar, Megha, Olsson, Anton M., Steel, Kathryn J.A., Georgouli, Mirella, Ranasinghe, Ushan, Brender Read, Christine, Frederiksen, Klaus S., Taams, Leonie S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397583/ https://www.ncbi.nlm.nih.gov/pubmed/28118944 http://dx.doi.org/10.1016/j.jaut.2017.01.002 |
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