Revealing Hidden Conformational Space of LOV Protein VIVID Through Rigid Residue Scan Simulations

VIVID(VVD) protein is a Light-Oxygen-Voltage(LOV) domain in circadian clock system. Upon blue light activation, a covalent bond is formed between VVD residue Cys108 and its cofactor flavin adenine dinucleotide(FAD), and prompts VVD switching from Dark state to Light state with significant conformati...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Hongyu, Zoltowski, Brian D., Tao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397860/
https://www.ncbi.nlm.nih.gov/pubmed/28425502
http://dx.doi.org/10.1038/srep46626

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397860/
https://www.ncbi.nlm.nih.gov/pubmed/28425502
http://dx.doi.org/10.1038/srep46626

Ejemplares similares