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Data Intensive Genome Level Analysis for Identifying Novel, Non-Toxic Drug Targets for Multi Drug Resistant Mycobacterium tuberculosis

We report the construction of a novel Systems Biology based virtual drug discovery model for the prediction of non-toxic metabolic targets in Mycobacterium tuberculosis (Mtb). This is based on a data-intensive genome level analysis and the principle of conservation of the evolutionarily important ge...

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Detalles Bibliográficos
Autores principales: Kaur, Divneet, Kutum, Rintu, Dash, Debasis, Brahmachari, Samir K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397868/
https://www.ncbi.nlm.nih.gov/pubmed/28425478
http://dx.doi.org/10.1038/srep46595