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YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor

YAP is a transcriptional co-regulator that plays important roles in various patho-physiological processes, including the survival and death of cells. However, the effect of YAP on apoptosis and EMT, simultaneously mediated by TGF-β1, is not known. In this study, we demonstrate that YAP can modulate...

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Detalles Bibliográficos
Autores principales: Liu, Yi, He, Kai, Hu, Ying, Guo, Xiaojie, Wang, Dongmei, Shi, Weiwei, Li, Jingsong, Song, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397873/
https://www.ncbi.nlm.nih.gov/pubmed/28425446
http://dx.doi.org/10.1038/srep45523