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YAP modulates TGF-β1-induced simultaneous apoptosis and EMT through upregulation of the EGF receptor
YAP is a transcriptional co-regulator that plays important roles in various patho-physiological processes, including the survival and death of cells. However, the effect of YAP on apoptosis and EMT, simultaneously mediated by TGF-β1, is not known. In this study, we demonstrate that YAP can modulate...
Autores principales: | Liu, Yi, He, Kai, Hu, Ying, Guo, Xiaojie, Wang, Dongmei, Shi, Weiwei, Li, Jingsong, Song, Jianguo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397873/ https://www.ncbi.nlm.nih.gov/pubmed/28425446 http://dx.doi.org/10.1038/srep45523 |
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