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SUV39H1 Reduction Is Implicated in Abnormal Inflammation in COPD

Chronic obstructive pulmonary disease(COPD) is characterized by enhanced chronic inflammation in the airways, lung parenchyma, and circulation. We investigated whether SUV39H1, a histone methyltransferase, is causatively implicated in the abnormal inflammation observed in COPD. The SUV39H1 and H3K9m...

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Detalles Bibliográficos
Autores principales: Chen, Tzu-Tao, Wu, Sheng-Ming, Ho, Shu-Chuan, Chuang, Hsiao-Chi, Liu, Chien-Ying, Chan, Yao-Fei, Kuo, Lu-Wei, Feng, Po-Hao, Liu, Wen-Te, Chen, Kuan-Yuan, Hsiao, Ta-Chih, Juang, Jer-Nan, Lee, Kang-Yun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397975/
https://www.ncbi.nlm.nih.gov/pubmed/28425504
http://dx.doi.org/10.1038/srep46667