Aptamer-mediated impairment of EGFR-integrin αvβ3 complex inhibits vasculogenic mimicry and growth of triple-negative breast cancers

Current treatment options for triple-negative breast cancers (TNBCs) is limited by the absence of well-defined biomarkers, excluding a targeted therapy. Notably, epidermal growth factor receptor (EGFR) is overexpressed in a great proportion of TNBCs and is a negative prognostic factor. In clinical t...

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Detalles Bibliográficos
Autores principales: Camorani, Simona, Crescenzi, Elvira, Gramanzini, Matteo, Fedele, Monica, Zannetti, Antonella, Cerchia, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397976/
https://www.ncbi.nlm.nih.gov/pubmed/28425453
http://dx.doi.org/10.1038/srep46659

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5397976/
https://www.ncbi.nlm.nih.gov/pubmed/28425453
http://dx.doi.org/10.1038/srep46659

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