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Efficient single step chromatographic purification of recombinant human antithrombin (rhAT) from Saccharomyces cerevisiae

Antithrombin (AT) is a glycoprotein that inactivates the several physiological target enzymes of coagulation system. The effect of purification strategies plays a crucial role in getting maximum recovery of yield, purity and biological activity of recombinant human antithrombin (rhAT). In the presen...

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Detalles Bibliográficos
Autores principales: Mallu, Maheswara Reddy, Vemula, Sandeep, Ronda, Srinivasa Reddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398195/
https://www.ncbi.nlm.nih.gov/pubmed/28330182
http://dx.doi.org/10.1007/s13205-016-0412-z