Cargando…

A resorcinarene for inhibition of Aβ fibrillation

Amyloid-β peptides (Aβ) fibrillation is the hallmark of Alzheimer's disease (AD). However, it has been challenging to discover potent agents in order to inhibit Aβ fibrillation. Herein, we demonstrated the effect of resorcinarene on inhibiting Aβ fibrillation in vitro via experimental and compu...

Descripción completa

Detalles Bibliográficos
Autores principales: Han, Xu, Park, Jiyong, Wu, Wei, Malagon, Andres, Wang, Lingyu, Vargas, Edgar, Wikramanayake, Athula, Houk, K. N., Leblanc, Roger M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398272/
https://www.ncbi.nlm.nih.gov/pubmed/28451317
http://dx.doi.org/10.1039/c6sc04854d