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Oncodomains: A protein domain-centric framework for analyzing rare variants in tumor samples
The fight against cancer is hindered by its highly heterogeneous nature. Genome-wide sequencing studies have shown that individual malignancies contain many mutations that range from those commonly found in tumor genomes to rare somatic variants present only in a small fraction of lesions. Such rare...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398485/ https://www.ncbi.nlm.nih.gov/pubmed/28426665 http://dx.doi.org/10.1371/journal.pcbi.1005428 |