Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis

PURPOSE: Oct4 was reported to be one of the most important pluripotency transcription factors in the biology of stem cells including cancer stem cells, and progressed malignant cells. Here we report the investigation of gene expression control of Oct4 by selected human microRNAs and the physiologica...

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Detalles Bibliográficos
Autores principales: Göhring, Axel R., Reuter, Stefanie, Clement, Joachim H., Cheng, Xinlai, Theobald, Jannick, Wölfl, Stefan, Mrowka, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398498/
https://www.ncbi.nlm.nih.gov/pubmed/28426762
http://dx.doi.org/10.1371/journal.pone.0174912

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398498/
https://www.ncbi.nlm.nih.gov/pubmed/28426762
http://dx.doi.org/10.1371/journal.pone.0174912

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