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Human microRNA-299-3p decreases invasive behavior of cancer cells by downregulation of Oct4 expression and causes apoptosis
PURPOSE: Oct4 was reported to be one of the most important pluripotency transcription factors in the biology of stem cells including cancer stem cells, and progressed malignant cells. Here we report the investigation of gene expression control of Oct4 by selected human microRNAs and the physiologica...
Autores principales: | Göhring, Axel R., Reuter, Stefanie, Clement, Joachim H., Cheng, Xinlai, Theobald, Jannick, Wölfl, Stefan, Mrowka, Ralf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398498/ https://www.ncbi.nlm.nih.gov/pubmed/28426762 http://dx.doi.org/10.1371/journal.pone.0174912 |
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