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Pdgfrb is a direct regulatory target of TGFβ signaling in atrioventricular cushion mesenchymal cells

Cushion formation is the initial step for the development of valvuloseptal structures in mammalian hearts. TGFβ signaling plays critical roles in multiple steps of cushion morphogenesis. We used a newly developed conditional immortal atrioventricular cushion mesenchymal cell line, tsA58-AVM, to iden...

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Detalles Bibliográficos
Autores principales: Peng, Yin, Yan, Shun, Chen, Dongquan, Cui, Xiangqin, Jiao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398542/
https://www.ncbi.nlm.nih.gov/pubmed/28426709
http://dx.doi.org/10.1371/journal.pone.0175791