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Pdgfrb is a direct regulatory target of TGFβ signaling in atrioventricular cushion mesenchymal cells
Cushion formation is the initial step for the development of valvuloseptal structures in mammalian hearts. TGFβ signaling plays critical roles in multiple steps of cushion morphogenesis. We used a newly developed conditional immortal atrioventricular cushion mesenchymal cell line, tsA58-AVM, to iden...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398542/ https://www.ncbi.nlm.nih.gov/pubmed/28426709 http://dx.doi.org/10.1371/journal.pone.0175791 |