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T140 blocks the SDF-1/CXCR4 signaling pathway and prevents cartilage degeneration in an osteoarthritis disease model

Osteoarthritis (OA) is one of the most common diseases affecting older people; however, there remains no effective targeted drug to combat OA. The aims of this study were (1) to explore the effect of T140 in regulating degeneration of articular cartilage in vivo by targeted blocking of the SDF-1/CXC...

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Detalles Bibliográficos
Autores principales: Wang, Kun, Li, Yanlin, Han, Rui, Cai, Guofeng, He, Chuan, Wang, Guoliang, Jia, Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398617/
https://www.ncbi.nlm.nih.gov/pubmed/28426786
http://dx.doi.org/10.1371/journal.pone.0176048