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T140 blocks the SDF-1/CXCR4 signaling pathway and prevents cartilage degeneration in an osteoarthritis disease model
Osteoarthritis (OA) is one of the most common diseases affecting older people; however, there remains no effective targeted drug to combat OA. The aims of this study were (1) to explore the effect of T140 in regulating degeneration of articular cartilage in vivo by targeted blocking of the SDF-1/CXC...
Autores principales: | Wang, Kun, Li, Yanlin, Han, Rui, Cai, Guofeng, He, Chuan, Wang, Guoliang, Jia, Di |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398617/ https://www.ncbi.nlm.nih.gov/pubmed/28426786 http://dx.doi.org/10.1371/journal.pone.0176048 |
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