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Observation of σ-pore currents in mutant hKv1.2_V370C potassium channels
Current through the σ-pore was first detected in hKv1.3_V388C channels, where the V388C mutation in hKv1.3 channels opened a new pathway (σ-pore) behind the central α-pore. Typical for this mutant channel was inward current at potentials more negative than -100 mV when the central α-pore was closed....
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398642/ https://www.ncbi.nlm.nih.gov/pubmed/28426823 http://dx.doi.org/10.1371/journal.pone.0176078 |