Cargando…

cAMP Signaling Enhances HIV-1 Long Terminal Repeat (LTR)-directed Transcription and Viral Replication in Bone Marrow Progenitor Cells

CD34(+) hematopoietic progenitor cells have been shown to be susceptible to HIV-1 infection, possibly due to a low-level expression of CXCR4, a coreceptor for HIV-1 entry. Given these observations, we have explored the impact of forskolin on cell surface expression of CXCR4 in a cell line model (TF-...

Descripción completa

Detalles Bibliográficos
Autores principales: Banerjee, Anupam, Li, Luna, Pirrone, Vanessa, Krebs, Fred C, Wigdahl, Brian, Nonnemacher, Michael R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398651/
https://www.ncbi.nlm.nih.gov/pubmed/28469516
http://dx.doi.org/10.1177/1179555717694535