Excessive dietary intake of vitamin A reduces skull bone thickness in mice

Calvarial thinning and skull bone defects have been reported in infants with hypervitaminosis A. These findings have also been described in humans, mice and zebrafish with loss-of-function mutations in the enzyme CYP26B1 that degrades retinoic acid (RA), the active metabolite of vitamin A, indicatin...

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Detalles Bibliográficos
Autores principales: Lind, Thomas, Öhman, Caroline, Calounova, Gabriela, Rasmusson, Annica, Andersson, Göran, Pejler, Gunnar, Melhus, Håkan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398668/
https://www.ncbi.nlm.nih.gov/pubmed/28426756
http://dx.doi.org/10.1371/journal.pone.0176217

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398668/
https://www.ncbi.nlm.nih.gov/pubmed/28426756
http://dx.doi.org/10.1371/journal.pone.0176217

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