CD8(+) T cell evasion mandates CD4(+) T cell control of chronic gamma-herpesvirus infection

Gamma-herpesvirus infections are regulated by both CD4(+) and CD8(+) T cells. However clinical disease occurs mainly in CD4(+) T cell-deficient hosts. In CD4(+) T cell-deficient mice, CD8(+) T cells control acute but not chronic lung infection by Murid Herpesvirus-4 (MuHV-4). We show that acute and...

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Detalles Bibliográficos
Autores principales: Tan, Cindy S. E., Lawler, Clara, Stevenson, Philip G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398720/
https://www.ncbi.nlm.nih.gov/pubmed/28394921
http://dx.doi.org/10.1371/journal.ppat.1006311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398720/
https://www.ncbi.nlm.nih.gov/pubmed/28394921
http://dx.doi.org/10.1371/journal.ppat.1006311

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