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CD8(+) T cell evasion mandates CD4(+) T cell control of chronic gamma-herpesvirus infection
Gamma-herpesvirus infections are regulated by both CD4(+) and CD8(+) T cells. However clinical disease occurs mainly in CD4(+) T cell-deficient hosts. In CD4(+) T cell-deficient mice, CD8(+) T cells control acute but not chronic lung infection by Murid Herpesvirus-4 (MuHV-4). We show that acute and...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398720/ https://www.ncbi.nlm.nih.gov/pubmed/28394921 http://dx.doi.org/10.1371/journal.ppat.1006311 |