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A Wnt-planar polarity pathway instructs neurite branching by restricting F-actin assembly through endosomal signaling

Spatial arrangement of neurite branching is instructed by both attractive and repulsive cues. Here we show that in C. elegans, the Wnt family of secreted glycoproteins specify neurite branching sites in the PLM mechanosensory neurons. Wnts function through MIG-1/Frizzled and the planar cell polarity...

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Detalles Bibliográficos
Autores principales: Chen, Chun-Hao, He, Chun-Wei, Liao, Chien-Po, Pan, Chun-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398721/
https://www.ncbi.nlm.nih.gov/pubmed/28384160
http://dx.doi.org/10.1371/journal.pgen.1006720