Stromal PTEN inhibits the expansion of mammary epithelial stem cells through Jagged-1

Fibroblasts within the mammary tumor microenvironment are active participants in carcinogenesis mediating both tumor initiation and progression. Our group has previously demonstrated that genetic loss of PTEN in mammary fibroblasts induces an oncogenic secretome that remodels the extracellular milie...

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Detalles Bibliográficos
Autores principales: Sizemore, GM, Balakrishnan, S, Hammer, AM, Thies, KA, Trimboli, AJ, Wallace, JA, Sizemore, ST, Kladney, RD, Woelke, SA, Yu, L, Fernandez, SA, Chakravarti, A, Leone, G, Ostrowski, MC
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398932/
https://www.ncbi.nlm.nih.gov/pubmed/27797378
http://dx.doi.org/10.1038/onc.2016.383

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398932/
https://www.ncbi.nlm.nih.gov/pubmed/27797378
http://dx.doi.org/10.1038/onc.2016.383

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