Wwox–Brca1 interaction: role in DNA repair pathway choice

In this study, loss of expression of the fragile site-encoded Wwox protein was found to contribute to radiation and cisplatin resistance of cells, responses that could be associated with cancer recurrence and poor outcome. WWOX gene deletions occur in a variety of human cancer types, and reduced Wwo...

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Detalles Bibliográficos
Autores principales: Schrock, M S, Batar, B, Lee, J, Druck, T, Ferguson, B, Cho, J H, Akakpo, K, Hagrass, H, Heerema, N A, Xia, F, Parvin, J D, Aldaz, C M, Huebner, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398941/
https://www.ncbi.nlm.nih.gov/pubmed/27869163
http://dx.doi.org/10.1038/onc.2016.389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5398941/
https://www.ncbi.nlm.nih.gov/pubmed/27869163
http://dx.doi.org/10.1038/onc.2016.389

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