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Cytoplasmic aryl hydrocarbon receptor regulates glycogen synthase kinase 3 beta, accelerates vimentin degradation, and suppresses epithelial–mesenchymal transition in non-small cell lung cancer cells

Aryl hydrocarbon receptor (AHR), a ligand-activated transcription factor, has been studied extensively in carcinogenesis through the genomic pathway. In recent years, AHR has also been reported to exert positive or negative effects on epithelial–mesenchymal transition (EMT), the crucial step in tumo...

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Detalles Bibliográficos
Autores principales: Li, Ching-Hao, Liu, Chen-Wei, Tsai, Chi-Hao, Peng, Yi-Jen, Yang, Yu-Hsuan, Liao, Po-Lin, Lee, Chen-Chen, Cheng, Yu-Wen, Kang, Jaw-Jou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399057/
https://www.ncbi.nlm.nih.gov/pubmed/27752740
http://dx.doi.org/10.1007/s00204-016-1870-0