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Type I and Type III Interferons Display Different Dependency on Mitogen-Activated Protein Kinases to Mount an Antiviral State in the Human Gut

Intestinal epithelial cells (IECs) are constantly exposed to commensal flora and pathogen challenges. How IECs regulate their innate immune response to maintain gut homeostasis remains unclear. Interferons (IFNs) are cytokines produced during infections. While type I IFN receptors are ubiquitously e...

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Detalles Bibliográficos
Autores principales: Pervolaraki, Kalliopi, Stanifer, Megan L., Münchau, Stephanie, Renn, Lynnsey A., Albrecht, Dorothee, Kurzhals, Stefan, Senís, Elena, Grimm, Dirk, Schröder-Braunstein, Jutta, Rabin, Ronald L., Boulant, Steeve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399069/
https://www.ncbi.nlm.nih.gov/pubmed/28484457
http://dx.doi.org/10.3389/fimmu.2017.00459