Mitochondrial DNA Mutations in Grade II and III Glioma Cell Lines Are Associated with Significant Mitochondrial Dysfunction and Higher Oxidative Stress

The role of mitochondria in tumorigenesis has regained much attention as it could dysregulate cellular energetics, oxidative stress and apoptosis. However, the role of mitochondria in different grade gliomasis still unknown. This study aimed to identify mitochondrial DNA (mtDNA) sequence variations...

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Detalles Bibliográficos
Autores principales: Soon, Bee Hong, Abdul Murad, Nor Azian, Then, Sue-Mian, Abu Bakar, Azizi, Fadzil, Farizal, Thanabalan, Jegan, Mohd Haspani, Mohd S., Toh, Charng Jeng, Mohd Tamil, Azmi, Harun, Roslan, Wan Ngah, Wan Z., Jamal, Rahman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399085/
https://www.ncbi.nlm.nih.gov/pubmed/28484394
http://dx.doi.org/10.3389/fphys.2017.00231

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399085/
https://www.ncbi.nlm.nih.gov/pubmed/28484394
http://dx.doi.org/10.3389/fphys.2017.00231

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