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Activity-Dependent Synaptic Refinement: New Insights from Drosophila

During development, neurons establish inappropriate connections as they seek out their synaptic partners, resulting in supernumerary synapses that must be pruned away. The removal of miswired synapses usually involves electrical activity, often through a Hebbian spike-timing mechanism. A novel form...

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Detalles Bibliográficos
Autores principales: Vonhoff, Fernando, Keshishian, Haig
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399093/
https://www.ncbi.nlm.nih.gov/pubmed/28484377
http://dx.doi.org/10.3389/fnsys.2017.00023