Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts

Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a membrane-bound MMP that is highly expressed in cells with invading capacity, including fibroblasts and invasive cancer cells. However, pathways of MT1-MMP up-regulation are not clearly understood. A potential physiological stimulus for MT1-MMP...

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Detalles Bibliográficos
Autores principales: Majkowska, Iwona, Shitomi, Yasuyuki, Ito, Noriko, Gray, Nathanael S., Itoh, Yoshifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2017
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399112/
https://www.ncbi.nlm.nih.gov/pubmed/28270508
http://dx.doi.org/10.1074/jbc.M116.770057

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399112/
https://www.ncbi.nlm.nih.gov/pubmed/28270508
http://dx.doi.org/10.1074/jbc.M116.770057

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