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Discoidin domain receptor 2 mediates collagen-induced activation of membrane-type 1 matrix metalloproteinase in human fibroblasts
Membrane-type 1 matrix metalloproteinase (MT1-MMP) is a membrane-bound MMP that is highly expressed in cells with invading capacity, including fibroblasts and invasive cancer cells. However, pathways of MT1-MMP up-regulation are not clearly understood. A potential physiological stimulus for MT1-MMP...
Autores principales: | Majkowska, Iwona, Shitomi, Yasuyuki, Ito, Noriko, Gray, Nathanael S., Itoh, Yoshifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399112/ https://www.ncbi.nlm.nih.gov/pubmed/28270508 http://dx.doi.org/10.1074/jbc.M116.770057 |
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