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In vitro characterization and inhibition of the interaction between ciprofloxacin and berberine against multidrug-resistant Klebsiella pneumoniae

Ciprofloxacin is a quinolone antibiotic used to treat Klebsiella pneumoniae infections in the clinic. Previous studies have demonstrated that berberine exhibits antibacterial activity and less acquired resistance related to efflux pumps. The multidrug efflux pump acrAB-tolC can be stimulated to expe...

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Detalles Bibliográficos
Autores principales: Zhou, Xiao-Yuan, Ye, Xiao-Guang, He, Li-Ting, Zhang, Su-Rong, Wang, Ruo-Lun, Zhou, Jun, He, Zhuo-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399161/
https://www.ncbi.nlm.nih.gov/pubmed/26932407
http://dx.doi.org/10.1038/ja.2016.15