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Afadin is localized at cell–cell contact sites in mesangial cells and regulates migratory polarity

In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, which is the pathological characteristic of mesangial...

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Detalles Bibliográficos
Autores principales: Tsurumi, Haruko, Kurihara, Hidetake, Miura, Kenichiro, Tanego, Atsushi, Ohta, Yasutaka, Igarashi, Takashi, Oka, Akira, Horita, Shigeru, Hattori, Motoshi, Harita, Yutaka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399166/
https://www.ncbi.nlm.nih.gov/pubmed/26568295
http://dx.doi.org/10.1038/labinvest.2015.133