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Afadin is localized at cell–cell contact sites in mesangial cells and regulates migratory polarity
In kidney glomeruli, mesangial cells provide structural support to counteract for expansile forces caused by pressure gradients and to regulate the blood flow. Glomerular injury results in proliferation and aberrant migration of mesangial cells, which is the pathological characteristic of mesangial...
| Autores principales: | , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399166/ https://www.ncbi.nlm.nih.gov/pubmed/26568295 http://dx.doi.org/10.1038/labinvest.2015.133 |