Altered Kv2.1 functioning promotes increased excitability in hippocampal neurons of an Alzheimer's disease mouse model

Altered neuronal excitability is emerging as an important feature in Alzheimer's disease (AD). Kv2.1 potassium channels are important modulators of neuronal excitability and synaptic activity. We investigated Kv2.1 currents and its relation to the intrinsic synaptic activity of hippocampal neur...

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Detalles Bibliográficos
Autores principales: Frazzini, V, Guarnieri, S, Bomba, M, Navarra, R, Morabito, C, Mariggiò, M A, Sensi, S L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399189/
https://www.ncbi.nlm.nih.gov/pubmed/26890139
http://dx.doi.org/10.1038/cddis.2016.18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399189/
https://www.ncbi.nlm.nih.gov/pubmed/26890139
http://dx.doi.org/10.1038/cddis.2016.18

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