The transcriptional coactivator PGC1α protects against hyperthermic stress via cooperation with the heat shock factor HSF1

Heat shock proteins (HSPs) are required for the clearance of damaged and aggregated proteins and have important roles in protein homeostasis. It has been shown that the heat shock transcription factor, HSF1, orchestrates the transcriptional induction of these stress-regulated chaperones; however, th...

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Detalles Bibliográficos
Autores principales: Xu, L, Ma, X, Bagattin, A, Mueller, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399192/
https://www.ncbi.nlm.nih.gov/pubmed/26890141
http://dx.doi.org/10.1038/cddis.2016.22

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399192/
https://www.ncbi.nlm.nih.gov/pubmed/26890141
http://dx.doi.org/10.1038/cddis.2016.22

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