The anti-apoptotic Bcl-2 family protein A1/Bfl-1 regulates neutrophil survival and homeostasis and is controlled via PI3K and JAK/STAT signaling

Neutrophil granulocytes are innate effector cells of the first line of defense against pyogenic bacteria. Neutrophil lifespan is short, is prolonged by pro-inflammatory stimuli, controls functionality of the cells and can determine tissue damage. Experimental analysis of primary neutrophils is diffi...

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Detalles Bibliográficos
Autores principales: Vier, J, Groth, M, Sochalska, M, Kirschnek, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399193/
https://www.ncbi.nlm.nih.gov/pubmed/26890142
http://dx.doi.org/10.1038/cddis.2016.23

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399193/
https://www.ncbi.nlm.nih.gov/pubmed/26890142
http://dx.doi.org/10.1038/cddis.2016.23

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