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Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68

In animal cells, the centrosome is the main microtubule-organizing centre where microtubules are nucleated and anchored. The centriole subdistal appendages (SDAs) are the key structures that anchor microtubules in interphase cells, but the composition and assembly mechanisms of SDAs are not well und...

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Detalles Bibliográficos
Autores principales: Huang, Ning, Xia, Yuqing, Zhang, Donghui, Wang, Song, Bao, Yitian, He, Runsheng, Teng, Junlin, Chen, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399293/
https://www.ncbi.nlm.nih.gov/pubmed/28422092
http://dx.doi.org/10.1038/ncomms15057