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Cerebrospinal fluid (CSF) biomarkers of iron status are associated with CSF viral load, antiretroviral therapy, and demographic factors in HIV-infected adults

BACKGROUND: HIV-associated neurocognitive disorder (HAND) remains common, despite antiretroviral therapy (ART). HIV dysregulates iron metabolism, but cerebrospinal fluid (CSF) levels of iron and iron-transport proteins in HIV-infected (HIV+) persons are largely unknown. The objectives of this study...

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Detalles Bibliográficos
Autores principales: Patton, Stephanie M., Wang, Quan, Hulgan, Todd, Connor, James R., Jia, Peilin, Zhao, Zhongming, Letendre, Scott L., Ellis, Ronald J., Bush, William S., Samuels, David C., Franklin, Donald R., Kaur, Harpreet, Iudicello, Jennifer, Grant, Igor, Kallianpur, Asha R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399327/
https://www.ncbi.nlm.nih.gov/pubmed/28427421
http://dx.doi.org/10.1186/s12987-017-0058-1