A non-canonical binding interface in the crystal structure of HIV-1 gp120 core in complex with CD4

Numerous crystal structures of HIV gp120 have been reported, alone or with receptor CD4 and cognate antibodies; however, no sole gp120/CD4 complex without stabilization by an antibody is available. Here, we report a crystal structure of the gp120/CD4 complex without the aid of an antibody from HIV-1...

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Detalles Bibliográficos
Autores principales: Duan, Liang-Wei, Zhang, Hui, Zhao, Meng-Ting, Sun, Ji-Xue, Chen, Wen-Li, Lin, Jian-Ping, Liu, Xin-Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399459/
https://www.ncbi.nlm.nih.gov/pubmed/28429756
http://dx.doi.org/10.1038/srep46733

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399459/
https://www.ncbi.nlm.nih.gov/pubmed/28429756
http://dx.doi.org/10.1038/srep46733

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